Exact Computational Analyses for Adaptive Designs
نویسندگان
چکیده
We show how to compute optimal designs and exact analyses of allocation rules for various sequential allocation problems. The problems we have solved include parameter estimation in an industrial scenario, and testing in a clinical trial. Our computational approach incorporates backward induction, dynamic programming, and a new technique of forward induction. By utilizing e cient algorithms and careful implementation, we are able to determine exact solutions to practical problems previously approached only through simulation or approximation.
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